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Small molecule mimetics of α-helical domain of IRAK2 attenuate the pro-inflammatory effects of IL-33 in asthma-like mouse models
Interleukin-33 (IL-33) and its receptor ST2 play important roles in airway inflammation and contribute to asthma onset and exacerbation. IL-33/ST2 signaling pathway recruits adapter protein myeloid differentiation primary response 88 (MyD88) to transduce intracellular signaling. MyD88 forms a comple...
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| Publicado no: | J Immunol |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5988972/ https://ncbi.nlm.nih.gov/pubmed/29728508 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1700693 |
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