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Role of HBx in hepatitis B virus persistence and its therapeutic implications

Chronic hepatitis B virus infection is a significant risk factor for cirrhosis and hepatocellular carcinoma. The HBx protein is required for virus replication, but the lack of robust infection models has hindered our understanding of HBx functions that could be targeted for antiviral purposes. We br...

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Publicado en:Curr Opin Virol
Main Authors: Slagle, Betty L., Bouchard, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado: 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5988931/
https://ncbi.nlm.nih.gov/pubmed/29454995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coviro.2018.01.007
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