Absence of hybridization with the wild-type and mutant rpoB probes in the Genotype MTBDRplus assay detects ‘disputed’ Rifampicin mutations

OBJECTIVE: Mycobacterium tuberculosis isolates that fail to hybridize to at least one rpoB wildtype or any mutation probe on the Genotype MTBDRplus strip are assumed Rifampicin-resistant. However, the precise mutation(s) are unknown. We sought to identify the mutations in isolates with such hybridiz...

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Detalhes bibliográficos
Publicado no:Clin Microbiol Infect
Main Authors: Abanda, Ngu Njei, Djieugoué, Josiane Yvonne, Khadka, Vedbar S., Pefura-Yone, Eric Walter, Mbacham, Wilfred Fon, Vernet, Guy, Penlap, Veronique Mbeng, Deng, Youping, Eyangoh, Sara Irene, Taylor, Diane Wallace, Leke, Rose Gana Fomban
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5988914/
https://ncbi.nlm.nih.gov/pubmed/29217277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmi.2017.11.021
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