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Successful Treatment with a High-dose Rifampin-containing Regimen for Pulmonary Tuberculosis with a Disputed rpoB Mutation

Mutations in the rpoB gene of Mycobacterium tuberculosis can result in resistance to rifampin. Among various mutations in the rpoB gene, some known as disputed rpoB mutations can cause low-level rifampin resistance. It has been suggested that a high-dose rifampin (20 mg/kg)-based regimen might be ef...

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Detalhes bibliográficos
Publicado no:Intern Med
Principais autores: Jeong, Dae Hyun, Kang, Ye Won, Kim, Jin Young, Han, Ji Soo, Jo, Kyung-Wook, Shim, Tae Sun
Formato: Artigo
Idioma:Inglês
Publicado em: The Japanese Society of Internal Medicine 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6288001/
https://ncbi.nlm.nih.gov/pubmed/29984742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2169/internalmedicine.9571-17
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