Phosphoglyceric acid mutase-1 contributes to oncogenic mTOR-mediated tumor growth and confers non-small cell lung cancer patients with poor prognosis

As a hallmark of cancer, the Warburg effect (aerobic glycolysis) confers a selective advantage for the survival and proliferation of cancer cells. Due to frequent aberration of upstream proto-oncogenes and tumor suppressors, hyperactive mammalian/mechanistic target of rapamycin (mTOR) is a potent in...

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Vydáno v:Cell Death Differ
Hlavní autoři: Sun, Qian, Li, Shuzhan, Wang, Yanan, Peng, Haiyong, Zhang, Xiying, Zheng, Yu, Li, Chunjia, Li, Li, Chen, Rongrong, Chen, Xinxin, Bai, Wenjing, Jiang, Xiangli, Liu, Liang, Wei, Feng, Wang, Boshi, Zhang, Yu, Li, Hui, Ren, Xiubao, Zhang, Hongbing
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5988759/
https://ncbi.nlm.nih.gov/pubmed/29362480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-017-0034-y
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