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The homeobox protein VentX reverts immune suppression in the tumor microenvironment

Immune suppression in the tumor microenvironment (TME) is a central obstacle to effective immunotherapy. Tumor-associated macrophages (TAMs) are key components of the TME. Although TAMs have been viewed as an ideal target of intervention to steer immunity in cancer treatment, the approach has been h...

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Bibliographic Details
Published in:Nat Commun
Main Authors: Le, Yi, Gao, Hong, Bleday, Ronald, Zhu, Zhenglun
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5988690/
https://ncbi.nlm.nih.gov/pubmed/29872044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-04567-0
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