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The homeobox protein VentX reverts immune suppression in the tumor microenvironment

Immune suppression in the tumor microenvironment (TME) is a central obstacle to effective immunotherapy. Tumor-associated macrophages (TAMs) are key components of the TME. Although TAMs have been viewed as an ideal target of intervention to steer immunity in cancer treatment, the approach has been h...

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Détails bibliographiques
Publié dans:Nat Commun
Auteurs principaux: Le, Yi, Gao, Hong, Bleday, Ronald, Zhu, Zhenglun
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5988690/
https://ncbi.nlm.nih.gov/pubmed/29872044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-04567-0
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