Set up of a protocol for rat plasma peptidomics in hemorrhagic shock model in presence of heparin

A preliminary mass spectrometry based shotgun protocol was set up to compare the peptidome of plasma samples from healthy and hemorrhagic shock rats with the aim of verifying the possible role of uncontrolled proteolytic activity in circulatory shock. Since the hemorrhagic shock model requires hepar...

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Detalhes bibliográficos
Publicado no:EuPA Open Proteom
Main Authors: Maffioli, Elisa, Aletti, Federico, Santagata, Fabiana, Negri, Armando, Santamaria, Marco H., De Lano, Frank A., Kistler, Erik B., Schmid-Schönbein, Geert W., Tedeschi, Gabriella
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
Assuntos:
Special Section: Proceedings of the 9th Annual EuPA Congress “Proteomics - Back to the Future” (June 23 - 28, 2015, Milano, Italy)
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5988501/
https://ncbi.nlm.nih.gov/pubmed/29900112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.euprot.2016.03.004
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