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A pharmaco-metabolomics approach in a clinical trial of ALS: Identification of predictive markers of progression

There is an urgent and unmet need for accurate biomarkers in Amyotrophic Lateral Sclerosis. A pharmaco-metabolomics study was conducted using plasma samples from the TRO19622 (olesoxime) trial to assess the link between early metabolomic profiles and clinical outcomes. Patients included in this tria...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Blasco, Hélène, Patin, Franck, Descat, Amandine, Garçon, Guillaume, Corcia, Philippe, Gelé, Patrick, Lenglet, Timothée, Bede, Peter, Meininger, Vincent, Devos, David, Gossens, Jean François, Pradat, Pierre-François
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5988280/
https://ncbi.nlm.nih.gov/pubmed/29870556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0198116
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