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A pharmaco-metabolomics approach in a clinical trial of ALS: Identification of predictive markers of progression.

There is an urgent and unmet need for accurate biomarkers in Amyotrophic Lateral Sclerosis. A pharmaco-metabolomics study was conducted using plasma samples from the TRO19622 (olesoxime) trial to assess the link between early metabolomic profiles and clinical outcomes. Patients included in this tria...

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Detalhes bibliográficos
Main Authors: Hélène Blasco, Franck Patin, Amandine Descat, Guillaume Garçon, Philippe Corcia, Patrick Gelé, Timothée Lenglet, Peter Bede, Vincent Meininger, David Devos, Jean François Gossens, Pierre-François Pradat
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2018-01-01
Colecção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC5988280?pdf=render
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