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Histidine(168) is crucial for ΔpH-dependent gating of the human voltage-gated proton channel, hH(V)1

We recently identified a voltage-gated proton channel gene in the snail Helisoma trivolvis, HtH(V)1, and determined its electrophysiological properties. Consistent with early studies of proton currents in snail neurons, HtH(V)1 opens rapidly, but it unexpectedly exhibits uniquely defective sensitivi...

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Detalhes bibliográficos
Publicado no:J Gen Physiol
Main Authors: Cherny, Vladimir V., Morgan, Deri, Thomas, Sarah, Smith, Susan M.E., DeCoursey, Thomas E.
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5987877/
https://ncbi.nlm.nih.gov/pubmed/29743300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201711968
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