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Histidine(168) is crucial for ΔpH-dependent gating of the human voltage-gated proton channel, hH(V)1

We recently identified a voltage-gated proton channel gene in the snail Helisoma trivolvis, HtH(V)1, and determined its electrophysiological properties. Consistent with early studies of proton currents in snail neurons, HtH(V)1 opens rapidly, but it unexpectedly exhibits uniquely defective sensitivi...

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Detalles Bibliográficos
Publicado en:J Gen Physiol
Main Authors: Cherny, Vladimir V., Morgan, Deri, Thomas, Sarah, Smith, Susan M.E., DeCoursey, Thomas E.
Formato: Artigo
Idioma:Inglês
Publicado: Rockefeller University Press 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5987877/
https://ncbi.nlm.nih.gov/pubmed/29743300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201711968
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