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Histidine(168) is crucial for ΔpH-dependent gating of the human voltage-gated proton channel, hH(V)1

We recently identified a voltage-gated proton channel gene in the snail Helisoma trivolvis, HtH(V)1, and determined its electrophysiological properties. Consistent with early studies of proton currents in snail neurons, HtH(V)1 opens rapidly, but it unexpectedly exhibits uniquely defective sensitivi...

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Bibliografske podrobnosti
izdano v:J Gen Physiol
Main Authors: Cherny, Vladimir V., Morgan, Deri, Thomas, Sarah, Smith, Susan M.E., DeCoursey, Thomas E.
Format: Artigo
Jezik:Inglês
Izdano: Rockefeller University Press 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5987877/
https://ncbi.nlm.nih.gov/pubmed/29743300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201711968
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