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Discrimination against RNA backbones by a ssDNA binding protein

Pot1 is the shelterin component responsible for the protection of the ssDNA overhang at telomeres in nearly all eukaryotic organisms. The C-terminal domain of the DNA-binding domain, Pot1pC, exhibits non-specific ssDNA recognition, achieved through thermodynamically equivalent alternative binding co...

詳細記述

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書誌詳細
出版年:Structure
主要な著者: Lloyd, Neil R., Wuttke, Deborah S.
フォーマット: Artigo
言語:Inglês
出版事項: 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5987771/
https://ncbi.nlm.nih.gov/pubmed/29681468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2018.03.016
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