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Discrimination against RNA backbones by a ssDNA binding protein
Pot1 is the shelterin component responsible for the protection of the ssDNA overhang at telomeres in nearly all eukaryotic organisms. The C-terminal domain of the DNA-binding domain, Pot1pC, exhibits non-specific ssDNA recognition, achieved through thermodynamically equivalent alternative binding co...
Guardat en:
| Publicat a: | Structure |
|---|---|
| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5987771/ https://ncbi.nlm.nih.gov/pubmed/29681468 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2018.03.016 |
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