Crystal structure of Escherichia coli purine nucleoside phosphorylase in complex with 7-deazahypoxanthine

Purine nucleoside phosphorylases (EC 2.4.2.1; PNPs) reversibly catalyze the phosphorolytic cleavage of glycosidic bonds in purine nucleosides to generate ribose 1-phosphate and a free purine base, and are key enzymes in the salvage pathway of purine biosynthesis. They also catalyze the transfer of p...

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Veröffentlicht in:Acta Crystallogr F Struct Biol Commun
Hauptverfasser: Timofeev, Vladimir I., Zhukhlistova, Nadezhda E., Abramchik, Yuliya A., Fateev, Ilya I., Kostromina, Maria A., Muravieva, Tatiana I., Esipov, Roman S., Kuranova, Inna P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: International Union of Crystallography 2018
Schlagworte:
Research Communications
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5987744/
https://ncbi.nlm.nih.gov/pubmed/29870020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X18006337
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