Aqp0a Regulates Suture Stability in the Zebrafish Lens

PURPOSE: To investigate the roles of Aquaporin 0a (Aqp0a) and Aqp0b in zebrafish lens development and transparency. METHODS: CRISPR/Cas9 gene editing was used to generate loss-of-function deletions in zebrafish aqp0a and/or aqp0b. Wild type (WT), single mutant, and double mutant lenses were analyzed...

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Udgivet i:Invest Ophthalmol Vis Sci
Main Authors: Vorontsova, Irene, Gehring, Ines, Hall, James E., Schilling, Thomas F.
Format: Artigo
Sprog:Inglês
Udgivet: The Association for Research in Vision and Ophthalmology 2018
Fag:
Lens
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5987579/
https://ncbi.nlm.nih.gov/pubmed/30025131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.18-24044
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