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Targeting mitochondrial responses to intra-articular fracture to prevent posttraumatic osteoarthritis
We tested whether inhibiting mechanically-responsive articular chondrocyte mitochondria after severe traumatic injury and preventing oxidative damage represent a viable paradigm for posttraumatic osteoarthritis (PTOA) prevention. We used a porcine hock intra-articular fracture (IAF) model well suite...
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| Pubblicato in: | Sci Transl Med |
|---|---|
| Autori principali: | , , , , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5987523/ https://ncbi.nlm.nih.gov/pubmed/29437147 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aan5372 |
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