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Prenatal Exposure to a Maternal High Fat Diet Increases Hepatic Cholesterol Accumulation in Intrauterine Growth Restricted Rats in Part Through MicroRNA-122 Inhibition of Cyp7a1

Intrauterine growth restriction (IUGR) and consumption of a high saturated fat diet (HFD) increase the risk of hypercholesterolemia, a leading cause of morbidity and mortality. The mechanism through which the cumulative impact of IUGR and in utero exposure to a maternal HFD increase cholesterol leve...

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Detalhes bibliográficos
Publicado no:Front Physiol
Main Authors: Zinkhan, Erin K., Yu, Baifeng, Schlegel, Amnon
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5987111/
https://ncbi.nlm.nih.gov/pubmed/29896121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2018.00645
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