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Increased ATP and ADO Overflow From Sympathetic Nerve Endings and Mesentery Endothelial Cells Plus Reduced Nitric Oxide Are Involved in Diabetic Neurovascular Dysfunction

Since the mechanism of human diabetic peripheral neuropathy and vascular disease in type 1 diabetes mellitus remains unknown, we assessed whether sympathetic transmitter overflow is altered by this disease and associated to vascular dysfunction. Diabetes was induced by streptozotocin (STZ)-treatment...

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Dades bibliogràfiques
Publicat a:Front Pharmacol
Autors principals: Donoso, M. Verónica, Mascayano, M. Jesús, Poblete, Inés M., Huidobro-Toro, J. Pablo
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5987002/
https://ncbi.nlm.nih.gov/pubmed/29896104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00546
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