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Increased ATP and ADO Overflow From Sympathetic Nerve Endings and Mesentery Endothelial Cells Plus Reduced Nitric Oxide Are Involved in Diabetic Neurovascular Dysfunction

Since the mechanism of human diabetic peripheral neuropathy and vascular disease in type 1 diabetes mellitus remains unknown, we assessed whether sympathetic transmitter overflow is altered by this disease and associated to vascular dysfunction. Diabetes was induced by streptozotocin (STZ)-treatment...

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Bibliografski detalji
Izdano u:Front Pharmacol
Glavni autori: Donoso, M. Verónica, Mascayano, M. Jesús, Poblete, Inés M., Huidobro-Toro, J. Pablo
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5987002/
https://ncbi.nlm.nih.gov/pubmed/29896104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00546
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