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Removing Background Co-occurrences of Transcription Factor Binding Sites Greatly Improves the Prediction of Specific Transcription Factor Cooperations

Today, it is well-known that in eukaryotic cells the complex interplay of transcription factors (TFs) bound to the DNA of promoters and enhancers is the basis for precise and specific control of transcription. Computational methods have been developed for the identification of potentially cooperatin...

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Detalhes bibliográficos
Publicado no:Front Genet
Main Authors: Meckbach, Cornelia, Wingender, Edgar, Gültas, Mehmet
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5986914/
https://ncbi.nlm.nih.gov/pubmed/29896218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2018.00189
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