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Removing Background Co-occurrences of Transcription Factor Binding Sites Greatly Improves the Prediction of Specific Transcription Factor Cooperations

Today, it is well-known that in eukaryotic cells the complex interplay of transcription factors (TFs) bound to the DNA of promoters and enhancers is the basis for precise and specific control of transcription. Computational methods have been developed for the identification of potentially cooperatin...

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Pubblicato in:Front Genet
Autori principali: Meckbach, Cornelia, Wingender, Edgar, Gültas, Mehmet
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5986914/
https://ncbi.nlm.nih.gov/pubmed/29896218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2018.00189
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