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Removing Background Co-occurrences of Transcription Factor Binding Sites Greatly Improves the Prediction of Specific Transcription Factor Cooperations

Today, it is well-known that in eukaryotic cells the complex interplay of transcription factors (TFs) bound to the DNA of promoters and enhancers is the basis for precise and specific control of transcription. Computational methods have been developed for the identification of potentially cooperatin...

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Détails bibliographiques
Publié dans:Front Genet
Auteurs principaux: Meckbach, Cornelia, Wingender, Edgar, Gültas, Mehmet
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5986914/
https://ncbi.nlm.nih.gov/pubmed/29896218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2018.00189
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