Artificial strain of human prions created in vitro

The molecular mechanism that determines under physiological conditions transmissibility of the most common human prion disease, sporadic Creutzfeldt-Jakob disease (sCJD) is unknown. We report the synthesis of new human prion from the recombinant human prion protein expressed in bacteria in reaction...

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Vydáno v:Nat Commun
Hlavní autoři: Kim, Chae, Xiao, Xiangzhu, Chen, Shugui, Haldiman, Tracy, Smirnovas, Vitautas, Kofskey, Diane, Warren, Miriam, Surewicz, Krystyna, Maurer, Nicholas R., Kong, Qingzhong, Surewicz, Witold, Safar, Jiri G.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5986862/
https://ncbi.nlm.nih.gov/pubmed/29867164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-04584-z
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