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Cell-free protein synthesis as a novel tool for directed glycoengineering of active erythropoietin

As one of the most complex post-translational modification, glycosylation is widely involved in cell adhesion, cell proliferation and immune response. Nevertheless glycoproteins with an identical polypeptide backbone mostly differ in their glycosylation patterns. Due to this heterogeneity, the mappi...

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書目詳細資料
發表在:Sci Rep
Main Authors: Zemella, Anne, Thoring, Lena, Hoffmeister, Christian, Šamalíková, Mária, Ehren, Patricia, Wüstenhagen, Doreen A., Kubick, Stefan
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5986796/
https://ncbi.nlm.nih.gov/pubmed/29867209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-26936-x
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