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Cell-free protein synthesis as a novel tool for directed glycoengineering of active erythropoietin

As one of the most complex post-translational modification, glycosylation is widely involved in cell adhesion, cell proliferation and immune response. Nevertheless glycoproteins with an identical polypeptide backbone mostly differ in their glycosylation patterns. Due to this heterogeneity, the mappi...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zemella, Anne, Thoring, Lena, Hoffmeister, Christian, Šamalíková, Mária, Ehren, Patricia, Wüstenhagen, Doreen A., Kubick, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5986796/
https://ncbi.nlm.nih.gov/pubmed/29867209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-26936-x
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