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Neutrophils induce macrophage anti-inflammatory reprogramming by suppressing NF-κB activation

Apoptotic cells modulate the function of macrophages to control and resolve inflammation. Here, we show that neutrophils induce a rapid and sustained suppression of NF-κB signalling in the macrophage through a unique regulatory relationship which is independent of apoptosis. The reduction of macroph...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Marwick, John A., Mills, Ross, Kay, Oliver, Michail, Kyriakos, Stephen, Jillian, Rossi, Adriano G., Dransfield, Ian, Hirani, Nikhil
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5986789/
https://ncbi.nlm.nih.gov/pubmed/29867198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0710-y
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