Activation of neutral sphingomyelinase 2 by starvation induces cell-protective autophagy via an increase in Golgi-localized ceramide

Autophagy is essential for optimal cell function and survival, and the entire process accompanies membrane dynamics. Ceramides are produced by different enzymes at different cellular membrane sites and mediate differential signaling. However, it remains unclear which ceramide-producing pathways/enzy...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Back, Moon Jung, Ha, Hae Chan, Fu, Zhicheng, Choi, Jong Min, Piao, Yongwei, Won, Jong Hoon, Jang, Ji Min, Shin, In Chul, Kim, Dae Kyong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5986760/
https://ncbi.nlm.nih.gov/pubmed/29867196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0709-4
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