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Development and Evaluation of an Optimal Human Single-Chain Variable Fragment-Derived BCMA-Targeted CAR T Cell Vector

B cell maturation antigen (BCMA) has recently been identified as an important multiple myeloma (MM)-specific target for chimeric antigen receptor (CAR) T cell therapy. In CAR T cell therapy targeting CD19 for lymphoma, host immune anti-murine CAR responses limited the efficacy of repeat dosing and p...

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書誌詳細
出版年:Mol Ther
主要な著者: Smith, Eric L., Staehr, Mette, Masakayan, Reed, Tatake, Ishan J., Purdon, Terence J., Wang, Xiuyan, Wang, Pei, Liu, Hong, Xu, Yiyang, Garrett-Thomson, Sarah C., Almo, Steven C., Riviere, Isabelle, Liu, Cheng, Brentjens, Renier J.
フォーマット: Artigo
言語:Inglês
出版事項: American Society of Gene & Cell Therapy 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5986730/
https://ncbi.nlm.nih.gov/pubmed/29678657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2018.03.016
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