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A quantitative characterization of interaction between prion protein with nucleic acids

Binding of recombinant prion protein with small highly structured RNAs, prokaryotic and eukaryotic prion protein mRNA pseudoknots, tRNA and polyA has been studied by the change in fluorescence anisotropy of the intrinsic tryptophan groups of the protein. The affinities of these RNAs to the prion pro...

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Pubblicato in:Biochem Biophys Rep
Autori principali: Bera, Alakesh, Biring, Sajal
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5986701/
https://ncbi.nlm.nih.gov/pubmed/29872743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2018.04.006
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