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Strikingly different effects of cholesterol and 7-ketocholesterol on lipid bilayer-mediated aggregation of amyloid beta (1-42)

Oxidized cholesterol has been widely reported to contribute to the pathogenesis of Alzheimer's disease (AD). However, the mechanism by which they affect the disease is not fully understood. Herein, we aimed to investigate the effect of 7-ketocholesterol (7keto) on membrane-mediated aggregation...

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Detalhes bibliográficos
Publicado no:Biochem Biophys Rep
Main Authors: Phan, Huong T.T., Shimokawa, Naofumi, Sharma, Neha, Takagi, Masahiro, Vestergaard, Mun'delanji C.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5986554/
https://ncbi.nlm.nih.gov/pubmed/29872741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2018.04.007
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