Forced differentiation in vitro leads to stress-induced activation of DNA damage response in hiPSC-derived chondrocyte-like cells

A human induced pluripotent stem cell line (GPCCi001-A) created by our group was differentiated towards chondrocyte-like cells (ChiPS) via monolayer culturing with growth factors. ChiPS are promising because they have the potential to be used in tissue engineering to regenerate articular cartilage....

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Библиографические подробности
Опубликовано в: :PLoS One
Главные авторы: Stelcer, Ewelina, Kulcenty, Katarzyna, Rucinski, Marcin, Jopek, Karol, Richter, Magdalena, Trzeciak, Tomasz, Suchorska, Wiktoria Maria
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2018
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5986142/
https://ncbi.nlm.nih.gov/pubmed/29864138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0198079
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