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Ionizing radiation exposure of stem cell-derived chondrocytes affects their gene and microRNA expression profiles and cytokine production

Human induced pluripotent stem cells (hiPSCs) can be differentiated into chondrocyte-like cells. However, implantation of these cells is not without risk given that those transplanted cells may one day undergo ionizing radiation (IR) in patients who develop cancer. We aimed to evaluate the effect of...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Stelcer, Ewelina, Kulcenty, Katarzyna, Rucinski, Marcin, Kruszyna-Mochalska, Marta, Skrobala, Agnieszka, Sobecka, Agnieszka, Jopek, Karol, Suchorska, Wiktoria Maria
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8021574/
https://ncbi.nlm.nih.gov/pubmed/33820914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-86230-1
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