Impact of OGT deregulation on EZH2 target genes FOXA1 and FOXC1 expression in breast cancer cells

Enhancer of zest homolog 2 (EZH2) is a histone methyltransferase which plays a crucial role in cancer progression by regulation of genes involved in cellular processes such as proliferation, invasion and self-renewal. Activity and biological function of EZH2 are regulated by posttranslational modifi...

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Bibliographic Details
Published in:PLoS One
Main Authors: Forma, Ewa, Jóźwiak, Paweł, Ciesielski, Piotr, Zaczek, Agnieszka, Starska, Katarzyna, Bryś, Magdalena, Krześlak, Anna
Format: Artigo
Language:Inglês
Published: Public Library of Science 2018
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5986130/
https://ncbi.nlm.nih.gov/pubmed/29864144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0198351
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