Expression of hypoxia inducible factor 1α and 2α and its association with vitamin C level in thyroid lesions

BACKGROUND: Cells adapt to hypoxia by transcriptional induction of genes that participate in regulation of angiogenesis, glucose metabolism and cell proliferation. The primary factors mediating cell response to low oxygen tension are hypoxia inducible factors (HIFs), oxygen-dependent transcription a...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Biomed Sci
Main Authors: Jóźwiak, Paweł, Ciesielski, Piotr, Zaczek, Agnieszka, Lipińska, Anna, Pomorski, Lech, Wieczorek, Marek, Bryś, Magdalena, Forma, Ewa, Krześlak, Anna
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2017
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5663109/
https://ncbi.nlm.nih.gov/pubmed/29084538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12929-017-0388-y
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