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Human Induced Pluripotent Stem Cell Production and Expansion from Blood using a Non-Integrating Viral Reprogramming Vector

We describe a method to transform blood lymphocytes into human induced pluripotent stem cells by delivering 4 transcription factors with a non-integrative virus. Using human peripheral blood mononuclear cells (PBMCs) as the source cell type for hiPSC reprogramming is advantageous since blood samples...

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Detalhes bibliográficos
Publicado no:Curr Protoc Mol Biol
Main Authors: Sharma, Arun, Mücke, Michael, Seidman, Christine E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5986089/
https://ncbi.nlm.nih.gov/pubmed/29851250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpmb.58
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