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An information theoretic framework reveals a tunable allosteric network in group II chaperonins

The ATP-dependent allosteric regulation of the ring-shaped Group II chaperonins remains ill-defined. Their complex oligomeric topology limited the success of structural techniques in suggesting allosteric determinants. Further, their high sequence conservation has hindered prediction of allosteric n...

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Detalhes bibliográficos
Publicado no:Nat Struct Mol Biol
Main Authors: Lopez, Tom, Dalton, Kevin, Tomlinson, Anthony, Pande, Vijay, Frydman, Judith
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5986071/
https://ncbi.nlm.nih.gov/pubmed/28741612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.3440
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