An integrated systems biology approach identifies TRIM25 as a key determinant of breast cancer metastasis

At the root of most fatal malignancies are aberrantly activated transcriptional networks that drive metastatic dissemination. Although individual metastasis-associated genes have been described, the complex regulatory networks presiding over the initiation and maintenance of metastatic tumours are s...

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Pubblicato in:Cell Rep
Autori principali: Walsh, Logan A., Alvarez, Mariano J., Sabio, Erich Y., Reyngold, Marsha, Makarov, Vladimir, Mukherjee, Suranjit, Lee, Ken-Wing, Desrichard, Alexis, Turcan, Şevin, Dalin, Martin G., Rajasekhar, Vinagolu K., Chen, Shuibing, Vahdat, Linda T., Califano, Andrea, Chan, Timothy A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5985663/
https://ncbi.nlm.nih.gov/pubmed/28813674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.07.052
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