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Evolutionary Rewiring of Human Regulatory Networks by Waves of Genome Expansion

Genome expansion is believed to be an important driver of the evolution of gene regulation. To investigate the role of a newly arising sequence in rewiring regulatory networks, we estimated the age of each region of the human genome by applying maximum parsimony to genome-wide alignments with 100 ve...

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Detalhes bibliográficos
Publicado no:Am J Hum Genet
Main Authors: Marnetto, Davide, Mantica, Federica, Molineris, Ivan, Grassi, Elena, Pesando, Igor, Provero, Paolo
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5985534/
https://ncbi.nlm.nih.gov/pubmed/29357977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2017.12.014
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