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Evolutionary Rewiring of Human Regulatory Networks by Waves of Genome Expansion

Genome expansion is believed to be an important driver of the evolution of gene regulation. To investigate the role of a newly arising sequence in rewiring regulatory networks, we estimated the age of each region of the human genome by applying maximum parsimony to genome-wide alignments with 100 ve...

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Библиографические подробности
Опубликовано в: :Am J Hum Genet
Главные авторы: Marnetto, Davide, Mantica, Federica, Molineris, Ivan, Grassi, Elena, Pesando, Igor, Provero, Paolo
Формат: Artigo
Язык:Inglês
Опубликовано: Elsevier 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5985534/
https://ncbi.nlm.nih.gov/pubmed/29357977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2017.12.014
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