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DNA-sensing inflammasomes: regulation of bacterial host defense and the gut microbiota
DNA sensors are formidable immune guardians of the host. At least 14 cytoplasmic DNA sensors have been identified in recent years, each with specialized roles in driving inflammation and/or cell death. Of these, AIM2 is a sensor of dsDNA, and forms an inflammasome complex to activate the cysteine pr...
Gespeichert in:
| Veröffentlicht in: | Pathog Dis |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5985483/ https://ncbi.nlm.nih.gov/pubmed/27056948 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/femspd/ftw028 |
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