Inherited DNA-Repair Defects in Colorectal Cancer

Colorectal cancer (CRC) heritability has been estimated to be around 30%. However, mutations in the known CRC-susceptibility genes explain CRC risk in fewer than 10% of affected individuals. Germline mutations in DNA-repair genes (DRGs) have recently been reported in CRC, but their contribution to C...

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Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Am J Hum Genet
Κύριοι συγγραφείς: AlDubayan, Saud H., Giannakis, Marios, Moore, Nathanael D., Han, G. Celine, Reardon, Brendan, Hamada, Tsuyoshi, Mu, Xinmeng Jasmine, Nishihara, Reiko, Qian, Zhirong, Liu, Li, Yurgelun, Matthew B., Syngal, Sapna, Garraway, Levi A., Ogino, Shuji, Fuchs, Charles S., Van Allen, Eliezer M.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Elsevier 2018
Θέματα:
Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5985280/
https://ncbi.nlm.nih.gov/pubmed/29478780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2018.01.018
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