Rapid sensing of l-leucine by human and murine hypothalamic neurons: Neurochemical and mechanistic insights

OBJECTIVE: Dietary proteins are sensed by hypothalamic neurons and strongly influence multiple aspects of metabolic health, including appetite, weight gain, and adiposity. However, little is known about the mechanisms by which hypothalamic neural circuits controlling behavior and metabolism sense pr...

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Publicado en:Mol Metab
Main Authors: Heeley, Nicholas, Kirwan, Peter, Darwish, Tamana, Arnaud, Marion, Evans, Mark L., Merkle, Florian T., Reimann, Frank, Gribble, Fiona M., Blouet, Clemence
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2018
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5985239/
https://ncbi.nlm.nih.gov/pubmed/29439854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2018.01.021
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