Rapid sensing of l-leucine by human and murine hypothalamic neurons: Neurochemical and mechanistic insights

OBJECTIVE: Dietary proteins are sensed by hypothalamic neurons and strongly influence multiple aspects of metabolic health, including appetite, weight gain, and adiposity. However, little is known about the mechanisms by which hypothalamic neural circuits controlling behavior and metabolism sense pr...

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Detalhes bibliográficos
Publicado no:Mol Metab
Main Authors: Heeley, Nicholas, Kirwan, Peter, Darwish, Tamana, Arnaud, Marion, Evans, Mark L., Merkle, Florian T., Reimann, Frank, Gribble, Fiona M., Blouet, Clemence
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5985239/
https://ncbi.nlm.nih.gov/pubmed/29439854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2018.01.021
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