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Gender Dependency in Streoselective Pharmacokinetics of Tramadol and Its Phase I Metabolites in Relation to CYP2D6 Phenotype in Iranian Population

The stereoselective pharmacokinetic of Tramadol (T) and its main metabolites concerning the influence of CYP2D6 phenotype and gender on the phase I metabolism of this compound was studied after administration of 100 mg single oral dose of racemic T to 24 male and female subjects. The pharmacokinetic...

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Publicado en:Iran J Pharm Res
Autores principales: Hosseinzadeh Ardakani, Yalda, Lavasani, Hoda, Rouini, Mohammad-Reza
Formato: Artigo
Lenguaje:Inglês
Publicado: Shaheed Beheshti University of Medical Sciences 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5985193/
https://ncbi.nlm.nih.gov/pubmed/29881433
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