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Pharmacokinetics of mirtazapine and its main metabolites after single intravenous and oral administrations in rats at two dose rates
BACKGROUND: Mirtazapine (MRZ) is a human antidepressant drug metabolized to 8-OH mirtazapine (8-OH) and dimethylmirtazapine (DMR) metabolites. Recently, this drug has been proposed as a potential analgesic for use in a multidrug analgesic regime in the context of veterinary medicine. The aim of this...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BioMed Central
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3896718/ https://ncbi.nlm.nih.gov/pubmed/24397986 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2008-2231-22-13 |
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