Loratadine-Loaded Thermoresponsive Hydrogel: Characterization and Ex-vivo Rabbit Cornea Permeability Studies

Poor bioavailability of ophthalmic drops is mainly due to drainage through the nasal-lacrimal duct and a very low permeability through corneal epithelium. The aim of our study was to prepare and characterize an ocular hydrogel of loratadine, as an example of a lipophilic drug, to increase drug conce...

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Bibliografske podrobnosti
izdano v:Iran J Pharm Res
Main Authors: Sharif Makhmalzadeh, Behzad, Salimi, Anayatollah, Niroomand, Aida
Format: Artigo
Jezik:Inglês
Izdano: Shaheed Beheshti University of Medical Sciences 2018
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5985164/
https://ncbi.nlm.nih.gov/pubmed/29881404
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