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Preparation and optimization of polymeric micelles as an oral drug delivery system for deferoxamine mesylate: in vitro and ex vivo studies

Deferoxamine mesylate (DFO) is administered as a slow subcutaneous or intravenous infusion due to its poor oral bioavailability and lack of dose proportionality. The aim of the present study was to prepare and optimize polymeric micelles containing DFO, as an oral drug delivery system for increasing...

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Detalhes bibliográficos
Publicado no:Res Pharm Sci
Main Authors: Salimi, Anayatollah, Sharif Makhmal Zadeh, Behzad, Kazemi, Moloud
Formato: Artigo
Idioma:Inglês
Publicado em: Wolters Kluwer - Medknow 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6714110/
https://ncbi.nlm.nih.gov/pubmed/31516506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/1735-5362.263554
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