The EndoC-βH1 cell line is a valid model of human beta cells and applicable for screenings to identify novel drug target candidates

OBJECTIVE: To characterize the EndoC-βH1 cell line as a model for human beta cells and evaluate its beta cell functionality, focusing on insulin secretion, proliferation, apoptosis and ER stress, with the objective to assess its potential as a screening platform for identification of novel anti-diab...

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書誌詳細
出版年:Mol Metab
主要な著者: Tsonkova, Violeta Georgieva, Sand, Fredrik Wolfhagen, Wolf, Xenia Asbæk, Grunnet, Lars Groth, Kirstine Ringgaard, Anna, Ingvorsen, Camilla, Winkel, Louise, Kalisz, Mark, Dalgaard, Kevin, Bruun, Christine, Fels, Johannes Josef, Helgstrand, Charlotte, Hastrup, Sven, Öberg, Fredrik Kryh, Vernet, Erik, Sandrini, Michael Paolo Bastner, Shaw, Allan Christian, Jessen, Carsten, Grønborg, Mads, Hald, Jacob, Willenbrock, Hanni, Madsen, Dennis, Wernersson, Rasmus, Hansson, Lena, Jensen, Jan Nygaard, Plesner, Annette, Alanentalo, Tomas, Petersen, Maja Borup Kjær, Grapin-Botton, Anne, Honoré, Christian, Ahnfelt-Rønne, Jonas, Hecksher-Sørensen, Jacob, Ravassard, Philippe, Madsen, Ole D., Rescan, Claude, Frogne, Thomas
フォーマット: Artigo
言語:Inglês
出版事項: Elsevier 2017
主題:
Original Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5985049/
https://ncbi.nlm.nih.gov/pubmed/29307512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2017.12.007
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