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Pdx1 Is Post-Translationally Modified In vivo and Serine 61 Is the Principal Site of Phosphorylation

Maintaining sufficient levels of Pdx1 activity is a prerequisite for proper regulation of blood glucose homeostasis and beta cell function. Mice that are haploinsufficient for Pdx1 display impaired glucose tolerance and lack the ability to increase beta cell mass in response to decreased insulin sig...

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Detaylı Bibliyografya
Asıl Yazarlar: Frogne, Thomas, Sylvestersen, Kathrine Beck, Kubicek, Stefan, Nielsen, Michael Lund, Hecksher-Sørensen, Jacob
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3324462/
https://ncbi.nlm.nih.gov/pubmed/22509401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035233
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