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The RhoGAP Stard13 controls insulin secretion through F-actin remodeling
OBJECTIVE: Actin cytoskeleton remodeling is necessary for glucose-stimulated insulin secretion in pancreatic β-cells. A mechanistic understanding of actin dynamics in the islet is paramount to a better comprehension of β-cell dysfunction in diabetes. Here, we investigate the Rho GTPase regulator Sta...
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| Publié dans: | Mol Metab |
|---|---|
| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Elsevier
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5985048/ https://ncbi.nlm.nih.gov/pubmed/29310936 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2017.12.013 |
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