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An Asymmetry in Monolayer Tension Regulates Lipid Droplet Budding Direction

Cells store excess energy in the form of neutral lipids that are synthesized and encapsulated within the endoplasmic reticulum intermonolayer space. The lipids next demix to form lipid droplets (LDs), which, surprisingly, bud off mostly toward the cytosol. This directional LD formation is critical t...

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Pubblicato in:Biophys J
Autori principali: Chorlay, Aymeric, Thiam, Abdou Rachid
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Biophysical Society 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5985028/
https://ncbi.nlm.nih.gov/pubmed/29414709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.12.014
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